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The boy was born with a condition called genetic mosaicism (46, XX/XY), or both male and female DNA, and the boy's parents inform House and the team that the boy is unaware of his condition. They chose a gender for him when he was born and raised him accordingly. However, when his condition worsens and his life is threatened, the parents wonder whether they made the right decision. Meanwhile, Cuddy and Wilson suspect something is wrong with House when he starts acting way too nice.
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It seems that Debbie only pays a visit to people if they are about to die and does so with alarming accuracy. While House dismisses Morgan as a nut job, he is intrigued by her theory on the kiss-of-death cat, and sets out to disprove it. When Morgan falls seriously ill, he and the team are forced to get to the bottom of both mysteries. Meanwhile, Taub struggles with his finances and reconnects with an old high school friend at the clinic whose business successes present Taub with an entrepreneurial opportunity he had not previously considered. House bribes the handyman to lie to the insurance company about his broken pipes. However, the bribe was bigger than the costs of the repair.
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He is brought to Princeton-Plainsboro Hospital, though he claims that he is getting better. House grows suspicious when he learns that the painter was fearful of a test involving the injection of a dye. It is later revealed that he is on three separate drug trials, which he was hiding from his girlfriend. Meanwhile, House continues to use Lucas to obtain information about his team and to learn more about Cuddy's personal life. The team encounters a teenage boy (Dominic Scott Kay) who collapsed from severe pelvic pain after playing basketball.
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A deaf 14-year-old boy, Seth (Ryan Lane), collapses in the middle of a wrestling match after "hearing" explosions. House suffers from lack of sleep, which causes him to hallucinate that Amber is with him, helping him to solve the case. House also plans Chase's bachelor party — much to the dismay of Cameron — with the help of Amber. But House soon realizes that Amber is dangerous, and that she is not helpful to the case when Cuddy calls him to let him know that his diagnosis was wrong. The team goes to the hospital after the bachelor party ends suddenly to figure out what is wrong with their patient — after they sober up. House and the team take on the case of a woman (Judith Scott) who collapsed in the middle of a cooking class.
How Cuddy Left House MD & Why She Didn't Return For The Finale - Screen Rant
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An older woman, Charlotte (Colleen Camp), who has been taking care of her husband Eddie (Meat Loaf) for the last six months, is rushed to Princeton-Plainsboro for treatment after collapsing at Eddie's deathbed from respiratory failure. The case is further complicated as Eddie's condition improves while Charlotte's deteriorates. Meanwhile, the team tries to deal with their grief over Kutner's sudden suicide. When a priest (Jimmi Simpson) who runs a homeless shelter sees a bleeding Jesus hovering at his doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship.
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Thirteen takes a woman (Angela Gots) with whom she had a one-night stand to Princeton-Plainsboro after the woman has a seizure in Thirteen's apartment. House and the team take on her case, House using it as an opportunity to explore Thirteen's personal life. Thirteen ends up finding out the patient only slept with her to get to House, who had been rejecting the woman as a patient for many years.
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House orders a pain assessment to rule out anything psychosomatic, and an environmental scan. House and the team take on the case of Nick Greenwald (Jay Karnes), a book editor who loses his inhibitions and starts insulting co-workers at a dinner party one night before falling ill. The team realizes Nick has frontal lobe disinhibition, which has caused him to lose his filter and vocalize all of his innermost thoughts, resulting in extremely insulting outbursts. As Nick's free speech leads to some amusing and insightful comments regarding the team, he must deal with the consequences of being unable to lie to his wife and everyone else important in his life. Meanwhile, House suspects Wilson and Taub are keeping something from him when he catches them both in a lie.
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The team resists, with Thirteen asking how he'd like to be cut off from Vicodin. Foreman once again tries to talk Thirteen into having a relationship. Kutner and Taub come in with the results which show that there's air near the patient's intestines. Kutner and Thirteen decide to do an angioplasty to find the blockages. House comes in to find his team believing they have solved the problem. However, House realizes the patient tried to inject air into a blood vessel to kill himself - the air they found wasn't a symptom.
The responses of the patient, wife and son are consistent. Foreman does the environmental scan with Thirteen and find more drugs than House uses. Foreman thinks Thirteen's avoiding him after they kissed. Thirteen makes it clear she doesn't want to drag down Foreman. They find quail and Thirteen thinks it's food poisoning but Taub thinks the profile shows the pain's psychosomatic. House thinks it's rhabdomyolysis from food poisoning and orders a biopsy of the patient's muscles.
Cuddy tries to adopt, but after House tries to convince her not to, the adoption falls through anyway. When House tries to show his condolences and Cuddy snaps at him for changing his tune, they embrace and kiss. Wilson realizes that the two are very attracted to each other and attempts to make them confront their feelings. We soon begin to realize that although they are both reluctant to begin a romantic relationship, both want the other to be more involved in their lives. However, the biggest change in Season 5 was the departure of Kal Penn from the series so he could take a position at the White House.
An agoraphobic man (Todd Louiso) falls ill and refuses to leave his home to be treated at the hospital. Therefore, House and the team go to his home to figure out what might be wrong. Cameron takes charge of the case as she had treated the patient in the past and she and the team figure out ways to treat him at his home. However, the patient's condition worsens and it becomes difficult to treat him at his home.
The man's condition deteriorates and his daughter also begins to experience more symptoms. Meanwhile, House finds out Cuddy is going to adopt a baby that is due in two weeks. However, the birth mother (Vanessa Zima) has a strange rash on her arm, so Cuddy takes on her case as both a doctor and a potential mother. Two months have passed since Amber Volakis's shocking death.
Painless is a fifth season episode of House which first aired on January 19, 2009. At Cameron's urging, House and the team take on the case of a man living with such severe chronic pain that he tries to kill himself, unable to go on after living for years without a diagnosis or any relief from his suffering. As they try to determine whether the man's pain is psychosomatic or caused by a physical disease, parallels between the patient and House's experiences with excruciating, prolonged pain become apparent. When the patient again attempts suicide under the team's care, their search for answers becomes urgent. Meanwhile, Foreman and Thirteen explore their now complicated relationship as they work together on the Huntington's disease clinical drug trial.
As a result, Foreman begins first to get concerned about her behavior, then starts to feel protective. It soon blooms into a romance, but House feels it is affecting their medical judgement and tries to make them break up. Wilson slowly starts to recover from Amber's untimely death, but begins to reevaluate his life and to contemplate resigning from his post at the hospital. House's original regret over his role in Amber's death seems to have worn off as instead of being supportive, he merely tries to convince Wilson that he is overreacting to the situation. The fifth season of House premiered on September 16, 2008 and ended on May 11, 2009.
House is coerced into going to his father's funeral despite his protests. His team takes on the case of a young woman (Samantha Quan) who collapsed while in China searching for her birth parents. House works with the team via cell phone, while Wilson drives him—reluctantly—to the funeral.
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